Self-assembling injectable peptide hydrogels for emerging treatment of ischemic stroke

Author:

Hong Andrew12345ORCID,Aguilar Marie-Isabel67345ORCID,Del Borgo Mark P.67345ORCID,Sobey Christopher G.89101112ORCID,Broughton Brad R. S.1314345ORCID,Forsythe John S.12345ORCID

Affiliation:

1. Department of Materials Science and Engineering

2. Monash Institute of Medical Engineering

3. Monash University

4. Clayton

5. Australia

6. Department of Biochemistry & Molecular Biology

7. Monash Biomedicine Discovery Institute

8. Vascular Biology and Immunopharmacology Group

9. Department of Physiology

10. Anatomy and Microbiology

11. La Trobe University

12. Bundoora

13. Cardiovascular & Pulmonary Pharmacology Group

14. Biomedicine Discovery Institute and Department of Pharmacology

Abstract

Ischaemic stroke remains one of the leading causes of death and disability worldwide, without any long-term effective treatments targeted at regeneration. This has led to developments of novel, biomaterial-based strategies using self-assembling peptide hydrogels.

Funder

Monash University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Reference130 articles.

1. A growing global burden

2. Pharmacological therapy of acute ischaemic stroke: Achievements and problems

3. The Concept of Ischemic Penumbra in Acute Stroke and Therapeutic Opportunities

4. Thresholds in cerebral ischemia - the ischemic penumbra.

5. G. Silva , W.Koroshetz , R.González and L. H.Schwamm , in Acute Ischemic Stroke – Imaging and Intervention , ed. R. González , J. Hirsch , M. Lev , P. Schaefer and L. H. Schwamm , Springer , Berlin , 2nd edn, 2011

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