Molecular glues for manipulating enzymes: trypsin inhibition by benzamidine-conjugated molecular glues-Reference-Cited by-同舟云学术

Molecular glues for manipulating enzymes: trypsin inhibition by benzamidine-conjugated molecular glues

Published:2015 Issue:5 Volume:6 Page:2802-2805
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Mogaki Rina¹²³⁴⁵,Okuro Kou¹²³⁴⁵,Aida Takuzo¹²³⁴⁵

Affiliation:

1. Department of Chemistry and Biotechnology

2. School of Engineering

3. The University of Tokyo

4. Tokyo 113-8656

5. Japan

Abstract

The inhibitory effect of benzamidine as blocker on the protease activity of trypsin is enhanced by covalent conjugation with bioadhesive molecular glue.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/SC/C5SC00524H

Reference29 articles.

1. Self-assembly and optically triggered disassembly of hierarchical dendron–virus complexes

2. Smart Vaults: Thermally-Responsive Protein Nanocapsules

3. A heparin-mimicking polymer conjugate stabilizes basic fibroblast growth factor

4. Protein-Triggered Supramolecular Disassembly: Insights Based on Variations in Ligand Location in Amphiphilic Dendrons

5. Enzymes Hosted in Reverse Micelles in Hydrocarbon Solution

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