Phosgene-free synthesis of polypeptides using activated urethane derivatives of α-amino acids: an efficient synthetic approach to hydrophilic polypeptides-Reference-Cited by-同舟云学术

Phosgene-free synthesis of polypeptides using activated urethane derivatives of α-amino acids: an efficient synthetic approach to hydrophilic polypeptides

Published:2014 Issue:56 Volume:4 Page:29890-29896
ISSN:2046-2069
Container-title:RSC Adv.
language:en
Short-container-title:RSC Adv.

Author:

Yamada Shuhei¹²³,Sudo Atsushi⁴⁵²⁶,Goto Mitsuaki¹²³,Endo Takeshi¹²³

Affiliation:

1. Molecular Engineering Institute

2. Kinki University

3. Iizuka, Japan

4. Department of Applied Chemistry

5. Faculty of Science and Engineering

6. Higashiosaka, Japan

Abstract

Polypeptide synthesis has been successfully achieved through polycondensation of activated urethane derivatives with amines, accompanied by the elimination of phenol and CO₂.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2014/RA/C4RA03315A

Reference18 articles.

1. Methodologies for preparation of synthetic block copolypeptides: materials with future promise in drug delivery

2. Design of Environment-Sensitive Supramolecular Assemblies for Intracellular Drug Delivery: Polymeric Micelles that are Responsive to Intracellular pH Change

3. Development of the polymer micelle carrier system for doxorubicin

4. Tissue Engineering--Current Challenges and Expanding Opportunities

5. Synthesis and Characterization of Elastin-Mimetic Protein Gels Derived from a Well-Defined Polypeptide Precursor

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