Pb(ii) binding to the brain specific mammalian metallothionein isoform MT3 and its isolated αMT3 and βMT3 domains

Author:

Pérez-Zúñiga Catalina12345,Leiva-Presa Àngels678910,Austin Rachel Narehood1112131415,Capdevila Mercè12345ORCID,Palacios Òscar12345ORCID

Affiliation:

1. Departament de Química

2. Facultat de Ciències

3. Universitat Autònoma de Barcelona

4. E-08193 Cerdanyola del Vallès

5. Spain

6. Aquatic Ecology Group

7. Departament de Biociències

8. Facultat de Ciències i Tecnologia

9. Universitat de Vic – Universitat Central de Catalunya

10. E-08500 Vic

11. Department of Chemistry

12. Barnard College

13. Columbia University

14. NY

15. USA

Abstract

MT3 can bind Pb2+ to form a variety of metallated Pb-MT3 species.

Funder

Ministerio de Economía y Competitividad

National Science Foundation

Generalitat de Catalunya

Publisher

Oxford University Press (OUP)

Subject

Metals and Alloys,Biochemistry,Biomaterials,Biophysics,Chemistry (miscellaneous)

Reference58 articles.

1. Widening perspectives of lead toxicity

2. I. Lehmann , U.Sack and J.Lehmann . Metal Ions Affecting the Immune System , in, Metal Ions in Life Sciences , ed. A. Sigel , H. Sigel and R. K. O. Sigel , 2011 , vol. 8, p. 157

3. H. R. Pohl , N.Roney and H. G.Abadin , Metal Ions Affecting the neurological System , in Metal Ions in Life Sciences , ed. A. Sigel , H. Sigel , and R. K. O. Sigel , RSC Publishing , Cambridge , 2011 , ch. 10, vol. 8, pp. 247–262

4. Effects of lead exposure on hippocampal metabotropic glutamate receptor subtype 3 and 7 in developmental rats

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