Synthesis and biological evaluation of pyrazolo–triazole hybrids as cytotoxic and apoptosis inducing agents-Reference-Cited by-同舟云学术

Synthesis and biological evaluation of pyrazolo–triazole hybrids as cytotoxic and apoptosis inducing agents

Published:2015 Issue:40 Volume:13 Page:10136-10149
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Srinivasa Reddy T.¹²³⁴⁵,Kulhari Hitesh¹²³⁴⁵,Ganga Reddy V.¹²³⁴,Subba Rao A. V.¹²³⁴,Bansal Vipul⁶⁷⁸⁹¹⁰^ORCID,Kamal Ahmed¹²³⁴⁵,Shukla Ravi⁶⁷⁸⁹¹⁰

Affiliation:

1. Medicinal Chemistry and Pharmacology

2. CSIR-Indian Institute of Chemical Technology

3. Hyderabad

4. India

5. IICT-RMIT Research Centre

6. Ian Potter NanoBioSensing Facility

7. Nano Biotechnology Research Laboratory

8. School of Applied Sciences

9. RMIT University

10. Melbourne

Abstract

A series of pyrazolo–triazole hybrids were designed and synthesized by combining the 1,3-diphenyl pyrazole and triazole scaffolds to obtain (1-benzyl-1H-1,2,3-triazol-4-yl)(1,3-diphenyl-1H-pyrazol-4-yl)methanones.

Funder

Council for Scientific and Industrial Research

Australian Research Council

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/OB/C5OB00842E

Reference32 articles.

1. Cancer statistics, 2013

2. Cancer multidrug resistance: mechanisms involved and strategies for circumvention using a drug delivery system

3. Tumor resistance to apoptosis

4. Apoptosis-based therapies

5. Pyrazole scaffold: A remarkable tool in the development of anticancer agents

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