Diselenide-crosslinked nanogels laden with gold nanoparticles and methotrexate for immunomodulation-enhanced chemotherapy and computed tomography imaging of tumors

Author:

Jia Bingyang1,Gao Yue1,Ouyang Zhijun1,Shen Siyan1,Shen Mingwu1ORCID,Shi Xiangyang12ORCID

Affiliation:

1. State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, Shanghai Engineering Research Center of Nano-Biomaterials and Regenerative Medicine, College of Biological Science and Medical Engineering, Donghua University, Shanghai 201620, China

2. CQM - Centro de Química da Madeira, Universidade da Madeira, Campus Universitário da Penteada, 9020-105 Funchal, Portugal

Abstract

Diselenide-crosslinked nanogels can be loaded with gold nanoparticles and methotrexate for immunomodulation-enhanced chemotherapy and computed tomography imaging of tumors.

Funder

National Natural Science Foundation of China

Science and Technology Commission of Shanghai Municipality

Chinesisch-Deutsche Zentrum für Wissenschaftsförderung

Fundamental Research Funds for the Central Universities

Fundação para a Ciência e a Tecnologia

Agência Regional para o Desenvolvimento da Investigação, Tecnologia e Inovação

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

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