Hepatoprotective activity of viscosine is mediated by attenuation of hepatic macrophages and iNOS expression in CCl4-intoxicated rats

Author:

Ali Hamid12345,Kabir Nurul678910,Shah Muhammad Raza1112131415,Muhammad Akhtar1617181920,Ali Safdar2122234,Mehmood Shahab124254,Ali Amjad2627234,Ali Abid2829303132,Jahan Azra3334354

Affiliation:

1. Department of Biosciences

2. COMSATS Institute of Information Technology

3. Islamabad-44000

4. Pakistan

5. Dr. Panjwani Center for Molecular Medicine and Drug Research

6. Institute of Biological Sciences

7. Faculty of Science

8. University of Malaya

9. 50603 Kuala Lumpur

10. Malaysia

11. HEJ

12. Research Institute of Chemistry

13. International Center for Chemical Sciences (ICCBS)

14. University of Karachi

15. Karachi-75270

16. Department of Chemistry

17. Faculty of Sciences

18. Mugla Sitki Kocman University

19. Kotekli-48121

20. Turkey

21. Pakistan Institute of Engineering and Applied Sciences

22. Nilore

23. Islamabad

24. Shaheed Zulfikar Ali Bhutto Institute of Science and Technology

25. Karachi-75600

26. Department of Biochemistry

27. Quaid-e-azam University

28. Laboratory of Germplasm and Molecular Genetics

29. Department of Vegetable Sciences

30. College of Agriculture and Biotechnology

31. Zhejiang University

32. Hangzhou 310029

33. Department of Zoology

34. Hazara University

35. Mansehra

Abstract

This study investigated the molecular mechanism(s) of the protective effects of aC-alkylated flavonoid, viscosine on an animal model of CCl4-induced hepatotoxicity.

Publisher

Oxford University Press (OUP)

Subject

Health, Toxicology and Mutagenesis,Toxicology

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