Synthesis, antimalarial activity, and target binding of dibenzazepine-tethered isoxazolines-Reference-Cited by-同舟云学术

Synthesis, antimalarial activity, and target binding of dibenzazepine-tethered isoxazolines

Published:2015 Issue:110 Volume:5 Page:90408-90421
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Vinay Kumar Koravangala S.¹²³⁴,Lingaraju Gejjalagere S.¹²³⁴,Bommegowda Yadaganahalli K.¹²³⁴,Vinayaka Ajjampura C.¹²³⁴,Bhat Pritesh⁵⁶⁷⁴,Pradeepa Kumara Challanayakanahally S.¹²³⁴,Rangappa Kanchugarakoppal S.¹²³⁴,Gowda D. Channe⁸⁹¹⁰¹¹,Sadashiva Maralinganadoddi P.¹²³⁴⁸

Affiliation:

1. Department of Chemistry

2. University of Mysore

3. Mysuru

4. India

5. Manipal College of Pharmaceutical Sciences

6. Manipal University

7. Manipal

8. Department of Biochemistry and Molecular Biology

9. Pennsylvania State University College of Medicine

10. Hershey

11. USA

Abstract

A series of dibenzazepine tethered 3,5-disubstituted isoxazolines was synthesized and evaluated for their antimalarial activity usingP. falciparum3D7 strain. Further, the potent molecules were assessed againstP. falciparumD6, W2 and 7G8 strains.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/RA/C5RA17926B

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