Self-assembly of amphiphilic anionic calix[4]arenes and encapsulation of poorly soluble naproxen and flurbiprofen

Author:

Barbera Lucia1234,Gattuso Giuseppe1234,Kohnke Franz H.1234,Notti Anna1234,Pappalardo Sebastiano1564,Parisi Melchiorre F.1234,Pisagatti Ilenia1234,Patanè Salvatore7234,Micali Norberto894,Villari Valentina894

Affiliation:

1. Dipartimento di Scienze Chimiche

2. Università di Messina

3. 98166 Messina

4. Italy

5. Università di Catania

6. 95125 Catania

7. Dipartimento di Fisica e di Scienze della Terra

8. CNR-IPCF Istituto per i Processi Chimico-Fisici

9. 98158 Messina

Abstract

The ability of an anionic calix[4]arene amphiphile to aggregate and to solubilize, as a result, the poorly water-soluble drugs naproxen and flurbiprofen is described.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

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