Small-molecule inhibitors of HIF-PHD2: a valid strategy to renal anemia treatment in clinical therapy-Reference-Cited by-同舟云学术

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Small-molecule inhibitors of HIF-PHD2: a valid strategy to renal anemia treatment in clinical therapy

Published:2016 Issue:7 Volume:7 Page:1271-1284
ISSN:2040-2503
Container-title:MedChemComm
language:en
Short-container-title:Med. Chem. Commun.

Author:

Wu Yue¹²³⁴⁵,Wang Nan¹²³⁴⁵,Lei Yonghua¹²³⁴⁵,Hu Tianhan¹²³⁴⁵,You Qidong¹²³⁴⁵,Zhang Xiaojin¹²³⁴⁵^ORCID

Affiliation:

1. State Key Laboratory of Natural Medicines

2. and Jiangsu Key Laboratory of Drug Design and Optimization

3. China Pharmaceutical University

4. Nanjing 210009

5. China

Abstract

Patients with chronic kidney diseases (CKD) always suffer from anemia with severe impacts on their quality of life.

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/MD/C6MD00240D

Reference84 articles.

1. Estimated GFR, Albuminuria, and Complications of Chronic Kidney Disease

2. Albuminuria as a Risk Factor for Anemia in Chronic Kidney Disease: Result from the KoreaN Cohort Study for Outcomes in Patients With Chronic Kidney Disease (KNOW-CKD)

3. How should we manage anaemia in patients with diabetes?

4. The HIF Pathway and Erythrocytosis

5. S7.7 The role of carbohydrate on the biological activity of erythropoietin

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1. Exploring the natural products chemical space through a molecular search to discover potential inhibitors that target the hypoxia-inducible factor (HIF) prolyl hydroxylase domain (PHD);Frontiers in Pharmacology;2023-08-21

2. Artificial intelligence-aided discovery of prolyl hydroxylase 2 inhibitors to stabilize hypoxia inducible factor-1α and promote angiogenesis;Chinese Chemical Letters;2023-02

3. A novel PHD2 inhibitor acteoside from Cistanche tubulosa induces skeletal muscle mitophagy to improve cancer-related fatigue;Biomedicine & Pharmacotherapy;2022-06

4. Zeolitic imidazolate framework-67 accelerates infected diabetic chronic wound healing;Chemical Engineering Journal;2022-02

5. Liposomal PHD2 Inhibitors and the Enhanced Efficacy in Stabilizing HIF-1α;Nanomaterials;2022-01-03

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