Human blood-labyrinth barrier on a chip: a unique <i>in vitro</i> tool for investigation of BLB properties-Reference-Cited by-同舟云学术

Human blood-labyrinth barrier on a chip: a unique in vitro tool for investigation of BLB properties

Published:2023 Issue:36 Volume:13 Page:25508-25517
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Sekulic Marijana¹^ORCID,Abdollahi Narjes¹,Graf Lukas²,Deigendesch Nikolaus³,Puche Raoul¹,Bodmer Daniel¹²,Petkovic Vesna¹^ORCID

Affiliation:

1. Department of Biomedicine, University Hospital Basel, University of Basel, Basel, Switzerland

2. Clinic for Otolaryngology, Head and Neck Surgery, University Hospital Basel, Basel, Switzerland

3. Institute of Pathology, University Hospital Basel, Switzerland

Abstract

Our organ-on-a-chip successfully recreates the structure and behaviour of the human blood-labyrinth barrier (BLB). This unique microfluidic device provides an optimal environment and the shear forces necessary for proper barrier formation.

Funder

Innosuisse - Schweizerische Agentur für Innovationsförderung

Freiwillige Akademische Gesellschaft

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/RA/D3RA04704K

Reference39 articles.

1. Hearing Loss in Adults

2. The Flaws and Human Harms of Animal Experimentation

3. Animal models in an age of personalized medicine

4. Delivery of therapeutics to the inner ear: The challenge of the blood-labyrinth barrier

5. Endothelial Cell, Pericyte, and Perivascular Resident Macrophage-Type Melanocyte Interactions Regulate Cochlear Intrastrial Fluid–Blood Barrier Permeability

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