Rapid evaluation of gold nanoparticle–lipid membrane interactions using a lipid/polydiacetylene vesicle sensor

Author:

Gu Congcong12345,Geng Yingying6789ORCID,Zheng Feng12345ORCID,Rotello Vincent M.6789ORCID

Affiliation:

1. Department of Pharmaceutical Analysis

2. China Pharmaceutical University

3. Nanjing 210009

4. China

5. Key Laboratory of Drug Quality Control and Pharmacovigilance

6. Department of Chemistry

7. University of Massachusetts Amherst

8. Amherst

9. USA

Abstract

Lipid/polydiacetylene vesicles serve as a sensor to rapidly measure the interactions between gold nanoparticles and lipid membranes. A colorimetric signal is generated upon membrane disturbance caused by gold nanoparticles.

Funder

Fundamental Research Funds for the Central Universities

National Institutes of Health

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

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