Characterization of N-linked intact glycopeptide signatures of plasma IgGs from patients with prostate carcinoma and benign prostatic hyperplasia for diagnosis pre-stratification

Author:

Zhang Yong12345,Lin Tianhai67345,Zhao Yang89101112,Mao Yonghong1334512,Tao Yiran1434512,Huang Yan12345,Wang Shisheng12345,Hu Liqiang12345,Cheng Jingqiu12345,Yang Hao12345ORCID

Affiliation:

1. Key Lab of Transplant Engineering and Immunology

2. MOH; West China-Washington Mitochondria and Metabolism Research Center; Frontiers Science Center for Disease-related Molecular Network

3. West China Hospital

4. Sichuan University

5. Chengdu 610041

6. Department of Urology

7. Institute of Urology

8. Mass Spectrometry Engineering Technology Research Center

9. Center for Advanced Measurement Science

10. National Institute of Metrology

11. Beijing 102206

12. China

13. Department of Thoracic Surgery

14. West China-California Research Center for Predictive Intervention Medicine

Abstract

The discovery of novel non-invasive biomarkers for discriminating between prostate carcinoma (PCa) patients and benign prostatic hyperplasia (BPH) patients is necessary to reduce the burden of biopsies, avoid overdiagnosis and improve quality of life.

Funder

National Natural Science Foundation of China

National Basic Research Program of China

China Postdoctoral Science Foundation

West China Hospital, Sichuan University

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

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