Nanoparticle delivery of chemosensitizers improve chemotherapy efficacy without incurring additional toxicity

Author:

Caster Joseph M.12345,Sethi Manish12345,Kowalczyk Sonya12345,Wang Edina12345,Tian Xi12345,Nabeel Hyder Sayed12345,Wagner Kyle T.12345,Zhang Ying-Ao12345,Kapadia Chintan12345,Man Au Kin12345,Wang Andrew Z.12345

Affiliation:

1. Laboratory of Nano- and Translational Medicine

2. Department of Radiation Oncology

3. Lineberger Comprehensive Cancer Center

4. Carolina Center for Cancer Nanotechnology Excellence

5. University of North Carolina at Chapel Hill

Abstract

We demonstrate proof of principle that nanoparticle delivery of chemosensitizers can improve efficacy of chemotherapy without increasing toxicity.

Funder

National Institutes of Health

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

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