De novo design of self-assembly hydrogels based on Fmoc-diphenylalanine providing drug release-Reference-Cited by-同舟云学术

De novo design of self-assembly hydrogels based on Fmoc-diphenylalanine providing drug release

Published:2021 Issue:41 Volume:9 Page:8686-8693
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Li Xiang¹²³,Zhang Huijun¹,Liu Lingyan¹,Cao Chunyan¹,Wei Peng⁴,Yi Xin⁴,Zhou Yifeng²^ORCID,Lv Qingyang³,Zhou Dongfang³^ORCID,Yi Tao¹⁴^ORCID

Affiliation:

1. Department of Chemistry, Fudan University, Shanghai 200438, P. R. China

2. School of Chemical and Environmental Engineering, Shanghai Institute of Technology, Shanghai 201418, P. R. China

3. China School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, P. R. China

4. State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Chemistry, Chemical Engineering and Biotechnology, Donghua University, Shanghai 201620, P. R. China

Abstract

We report a self-assembly hydrogel formed under mild conditions based on Fmoc-FF by modifying its hydrophilicity. The hydrogel is elastic, reversible and injectable and can be used as a carrier to carry drugs into cancer cells.

Funder

National Natural Science Foundation of China

Fundamental Research Funds for the Central Universities

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2021/TB/D1TB01628H

Reference46 articles.

1. Polypeptide-based self-healing hydrogels: Design and biomedical applications

2. Self‐Healing and Injectable Hydrogel for Matching Skin Flap Regeneration