An ultrasmall PVP–Fe–Cu–Ni–S nano-agent for synergistic cancer therapy through triggering ferroptosis and autophagy-Reference-Cited by-同舟云学术

An ultrasmall PVP–Fe–Cu–Ni–S nano-agent for synergistic cancer therapy through triggering ferroptosis and autophagy

Published:2023 Issue:30 Volume:15 Page:12598-12611
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

Zhang Rongjun¹,Xu Shuxiang²³,Yuan Miaomiao⁴⁵^ORCID,Guo Lihao⁴,Xie Luoyijun⁵,Liao Yingying⁵,Xu Yang²³,Fu Xuemei⁶

Affiliation:

1. Institute of Molecular Medicine (IMM), Renji Hospital, State Key Laboratory of Oncogenes and Related Genes, Shanghai Jiao Tong University School of Medicine, Shanghai 200240, China

2. Department of Cardiology, Cardiovascular Key Lab of Zhejiang Province, The Second Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang University, Hangzhou, Zhejiang 310009, China

3. Binjiang Research Institute of Zhejiang University, Hangzhou, Zhejiang 310052, China

4. Precision Research Center for Refractory Diseases in Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China

5. The Eighth Affiliated Hospital, Sun Yat-sen University, Shenzhen, Guangdong 518033, China

6. International Peace Maternity and Child Health Hospital of China Welfare Institution, School of Medicine, Shanghai Jiao Tong University, Shanghai 200030, China

Abstract

We have synthesized an ultrasmall Fe–Cu–Ni–S nano-agent with excellent photothermal conversion efficiency (∼96%), which can be applied for MRI-guided synergistic PTT/PDT/CDT of cancers through triggering ferroptosis and autophagy.

Funder

National Key Research and Development Program of China

Sanming Project of Medicine in Shenzhen

Shenzhen Science and Technology Innovation Program

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2023/NR/D3NR02708B

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