Construction of novel multifunctional luminescent nanoparticles based on DNA bridging and their inhibitory effect on tumor growth

Author:

Pan Qiaobei1234,Zhang Jing56234ORCID,Li Xiang7234,Zou Qian7234,Zhang Peng56234,Luo Ying56234,Jin Yi1234

Affiliation:

1. National Pharmaceutical Engineering Center for Solid Preparation in Chinese Herbal Medicine

2. Jiangxi University of Traditional Chinese Medicine

3. Nanchang

4. People's Republic of China

5. Key Laboratory of Modern Preparation of TCM

6. Ministry of Education

7. State Key Laboratory of Innovative Drug and Efficient Energy-Saving Pharmaceutical Equipment

Abstract

Cyclic RGD peptide was introduced onto the surface of silver nanoparticle (AgNP)-single strand DNA (ssDNA)-graphene quantum dots (GQDs) (ADG) after coating with a hybrid phospholipid material (ADG-DDPC) to be used for antitumor treatment.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Jiangxi Province

China Postdoctoral Science Foundation

Health and Family Planning Commission of Jiangxi Province

Youth Science Foundation of Jiangxi Province

Jiangxi University of Traditional Chinese Medicine

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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