Metal substrate catalysis in the confined space for platinum drug delivery-Reference-Cited by-同舟云学术

Metal substrate catalysis in the confined space for platinum drug delivery

Published:2022 Issue:1 Volume:13 Page:59-67
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Velasco-Lozano Susana¹^ORCID,Castro Silvia Alonso-de²^ORCID,Sanchez-Cano Carlos¹²³^ORCID,Benítez-Mateos Ana I.¹^ORCID,López-Gallego Fernando¹³^ORCID,Salassa Luca²³⁴^ORCID

Affiliation:

1. Center for Cooperative Research in Biomaterials (CIC biomaGUNE), Basque Research and Technology Alliance (BRTA), Paseo de Miramon 182, San Sebastián, 20014, Spain

2. Donostia International Physics Center, Paseo Manuel de Lardizabal 4, Donostia, 20018, Spain

3. Ikerbasque, Basque Foundation for Science, Bilbao, 48011, Spain

4. Polimero eta Material Aurreratuak: Fisika, Kimika eta Teknologia, Kimika Fakultatea, Euskal Herriko Unibertsitatea UPV/EHU, Paseo Manuel de Lardizabal 3, Donostia, 20018, Spain

Abstract

Loading of a flavin catalyst and Pt prodrug onto a hydrogel affords biomaterials for the catalytic generation and delivery of cisplatin upon light irradiation or addition of electron donors. Confinement boosts the turnover frequency of the flavin.

Funder

Eusko Jaurlaritza

Consejo Nacional de Ciencia y Tecnología

H2020 European Research Council

Ministerio de Ciencia e Innovación

Diputación Foral de Gipuzkoa

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/SC/D1SC05151B