Comparative studies on the interaction of anticancer drug irinotecan with dsDNA and ssDNA-Reference-Cited by-同舟云学术

Comparative studies on the interaction of anticancer drug irinotecan with dsDNA and ssDNA

Published:2018 Issue:45 Volume:8 Page:25387-25395
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Temerk Yassien¹²³⁴⁵^ORCID,Ibrahim Mohamed⁶⁷⁸⁹¹⁰^ORCID,Ibrahim Hossieny¹²³⁴⁵^ORCID,Schuhmann Wolfgang¹¹¹²¹³¹⁴^ORCID

Affiliation:

1. Chemistry Department

2. Faculty of Science

3. Assiut University

4. Assiut

5. Egypt

6. Department of Clinical Pharmacy Research

7. Institute for Research and Medical Consultation

8. Imam Abdulrahman Bin Faisal University

9. Dammam 31441

10. Saudi Arabia

11. Anal. Chem. – Elektroanalytik & Sensorik

12. Ruhr-Universitat Bochum

13. D-44780 Bochum

14. Germany

Abstract

The binding mode and thermodynamic characteristics of the anticancer drug irinotecan (Irino) with dsDNA were investigated. The interaction of Irino with dsDNA indicated its intercalation into the base stacking domain of dsDNA double helix.

Funder

Alexander von Humboldt-Stiftung

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/RA/C8RA03231A

Reference50 articles.

1. Drug–DNA interactions and their study by UV–Visible, fluorescence spectroscopies and cyclic voltametry

2. Electrochemical approach of anticancer drugs–DNA interaction

3. Capillary electrophoresis for studying drug–DNA interactions

4. Using Microchip Gel Electrophoresis to Probe DNA–Drug Binding Interactions

5. DNA-based electrochemical biosensors for monitoring of bis-indoles as potential antitumoral agents, chemistry, X-ray crystallography

Cited by 23 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Electrochemical detection of bicalutamide in sepiolite clay sensing platform: Its possible electrooxidation mechanism, determination, and DNA interaction;Electroanalysis;2024-03-11

2. Mechanism of DNA Intercalation by Chloroquine Provides Insights into Toxicity;International Journal of Molecular Sciences;2024-01-24

3. A novel dsDNA decamer-based electrochemical biosensor for selective determination of irinotecan active metabolite - SN38;Sensors and Actuators B: Chemical;2023-12

4. Multi-spectroscopic and molecular simulation methods of analysis to explore the mode of binding of Mebendazole drug with calf-thymus DNA;Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy;2023-11

5. Application of Disposable Biosensor for Nivolumab–DNA Interaction Using Pencil Graphite Electrode;Russian Journal of Electrochemistry;2023-11