High-throughput mechanotransduction in Drosophila embryos with mesofluidics
Author:
Affiliation:
1. Department of Biological Sciences
2. Carnegie Mellon University
3. Pittsburgh
4. USA
5. Department of Mechanical Engineering
Abstract
A mesofluidic device allows alignment, immobilization, compression, imaging, and recovery of hundreds of live Drosophila embryos to investigate mechanotransduction.
Funder
Air Force Office of Scientific Research
Office of Naval Research
Pennsylvania Department of Health
Publisher
Royal Society of Chemistry (RSC)
Subject
Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering
Link
http://pubs.rsc.org/en/content/articlepdf/2019/LC/C8LC01055B
Reference66 articles.
1. Mechanotransduction's Impact on Animal Development, Evolution, and Tumorigenesis
2. Is mechano-sensitive expression of twist involved In mesoderm formation?
3. Interplay of mechanical deformation and patterned gene expression in developing embryos
4. Cell movements during gastrulation: Snail dependent and independent pathways
5. A putative cell signal encoded by the folded gastrulation gene coordinates cell shape changes during Drosophila gastrulation
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