Synthesis of grafted phosphorylcholine polymer layers as specific recognition ligands for C-reactive protein focused on grafting density and thickness to achieve highly sensitive detection-Reference-Cited by-同舟云学术

Synthesis of grafted phosphorylcholine polymer layers as specific recognition ligands for C-reactive protein focused on grafting density and thickness to achieve highly sensitive detection

Published:2015 Issue:15 Volume:17 Page:9951-9958
ISSN:1463-9076
Container-title:Physical Chemistry Chemical Physics
language:en
Short-container-title:Phys. Chem. Chem. Phys.

Author:

Kamon Yuri¹²³⁴,Kitayama Yukiya¹²³⁴,Itakura Akiko N.⁵⁶⁴,Fukazawa Kyoko⁷⁸⁹¹⁰⁴,Ishihara Kazuhiko⁷⁸⁹¹⁰⁴,Takeuchi Toshifumi¹²³⁴

Affiliation:

1. Graduate School of Engineering

2. Kobe University

3. Kobe 657-8501

4. Japan

5. National Institute for Materials Science

6. Tsukuba

7. Department of Materials Engineering

8. School of Engineering

9. The University of Tokyo

10. Bunkyo-ku

Abstract

We studied the effects of layer thickness and grafting density of poly(2-methacryloyloxyethyl phosphorylcholine) (PMPC) thin layers as specific ligands for the highly sensitive binding of C-reactive protein (CRP).

Publisher

Royal Society of Chemistry (RSC)

Subject

Physical and Theoretical Chemistry,General Physics and Astronomy

Link

http://pubs.rsc.org/en/content/articlepdf/2015/CP/C5CP00469A

Reference49 articles.

1. C-reactive protein and coronary heart disease: a critical review

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