Concise asymmetric total synthesis of catunaregin-Reference-Cited by-同舟云学术

Concise asymmetric total synthesis of catunaregin

Published:2016 Issue:9 Volume:3 Page:1084-1086
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Abe Hideki¹²³⁴,Hikichi Takuma¹²³⁴,Emori Kosuke¹²³⁴,Kobayashi Toyoharu¹²³⁴,Ito Hisanaka¹²³⁴

Affiliation:

1. School of Life Sciences

2. Tokyo University of Pharmacy and Life Sciences

3. Tokyo 192-0392

4. Japan

Abstract

The asymmetric total synthesis of the optically pure catunaregin was accomplished in 7 steps from a known methyl ester using an asymmetric syn-selective aldol reaction and the successive ketalization of a furan diol derivative under acidic conditions.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/QO/C6QO00213G

Reference11 articles.

1. An update on lignans: natural products and synthesis

2. An update on bioactive plant lignans

3. Catunaregin and Epicatunaregin, Two Norneolignans Possessing an Unprecedented Skeleton fromCatunaregam spinosa

4. Marine Compound Catunaregin Inhibits Angiogenesis through the Modulation of Phosphorylation of Akt and eNOS in vivo and in vitro

5. Synthesis of Tri- and Tetrasubstituted Furans Catalyzed by Trifluoroacetic Acid

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