Quantification of blood–brain barrier transport and neuronal toxicity of unlabelled multiwalled carbon nanotubes as a function of surface charge

Author:

Gonzalez-Carter Daniel12345ORCID,Goode Angela E.1234,Kiryushko Darya12345ORCID,Masuda Seigo1234,Hu Sheng6234ORCID,Lopes-Rodrigues Rosalia1234,Dexter David T.57823,Shaffer Milo S. P.12346,Porter Alexandra E.1234ORCID

Affiliation:

1. Department of Materials

2. Imperial College London

3. London

4. UK

5. Centre for Neuroinflammation and Neurodegeneration

6. Department of Chemistry

7. Division of Brain Sciences

8. Department of Medicine

Abstract

Directly and accurately characterizing the transport of nanoparticles across the blood–brain barrier will greatly advance the delivery of therapies against brain disorders.

Funder

H2020 European Research Council

H2020 Marie Skłodowska-Curie Actions

Michael J. Fox Foundation for Parkinson's Research

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

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