Developing an improved optical biosensing system based on gold nanoparticles acting as interferometric enhancers in Lactoferrin detection

Author:

Valle L. G.12ORCID,Santamaría B.123ORCID,Lavín A.124ORCID,Laguna M. F.124ORCID,Rodriguez-Lorenzo L.5ORCID,Espiña B.5ORCID,Holgado M.124ORCID

Affiliation:

1. Group of Optics, Photonics, and Biophotonics, Center for Biomedical Technology (CTB), Universidad Politécnica de Madrid, Parque Científico y Tecnológico de la UPM, Campus de Montegancedo, 28223 Pozuelo de Alarcón, Madrid, Spain

2. Group of Organ and Tissue on-a-chip and In-Vitro Detection, Health Research Institute of the Hospital Clínico San Carlos, IdISSC, C/Profesor Martín Lagos s/n, 4ª Planta Sur 28040, Madrid, Spain

3. Department of Mechanics, Chemistry and Industrial Design Engineering, Escuela Superior de Ingeniería y Diseño Industrial, Universidad Politécnica de Madrid, Ronda de Valencia 3, 28012, Madrid, Spain

4. Department of Applied Physics and Materials Engineering, Escuela Técnica Superior de Ingenieros Industriales, Universidad Politécnica de Madrid, C/José Gutiérrez Abascal, 2, 28006 Madrid, Spain

5. INL – International Iberian Nanotechnology Laboratory, Avda. Mestre Jose Veiga s/n, Braga, Portugal

Abstract

Antibody-coated goldnanoparticles (AuNPs) act as an interferometric enhancer, and their characterization, modeling, and comparison with ELISA.

Funder

European Commission

Ministerio de Ciencia e Innovación

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

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