High drug-loading system of hollow carbon dots–doxorubicin: preparation, in vitro release and pH-targeted research

Author:

Zhang Zedi1234,Lei Yuhua5674,Yang Xiaohong1234,Shi Nana1234,Geng Lina1234ORCID,Wang Shuping1234,Zhang Jianjun8234,Shi Shikao1234

Affiliation:

1. College of Chemistry and Material Science

2. Hebei Normal University

3. Shijiazhuang 050024

4. P. R. China

5. College of Basic Medicine

6. Hebei Medical University

7. Shijiazhuang 050017

8. Testing and Analysis Center

Abstract

HCDs–DOX was prepared with low cytotoxicity, and sustained, pH-targeted release properties. In vitro release conformed to the Weibull model and Fick diffusion.

Funder

Hebei Normal University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

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