Glycan–glycan interactions determine Leishmania attachment to the midgut of permissive sand fly vectors-Reference-Cited by-同舟云学术

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Glycan–glycan interactions determine Leishmania attachment to the midgut of permissive sand fly vectors

Published:2020 Issue:40 Volume:11 Page:10973-10983
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Hall Amy R.¹²³⁴⁵^ORCID,Blakeman Jamie T.¹²³⁴^ORCID,Eissa Ahmed M.⁶⁷⁸⁴^ORCID,Chapman Paul¹²³⁴⁶,Morales-García Ana L.¹²³⁴^ORCID,Stennett Laura⁹¹⁰¹¹¹²⁴,Martin Oihane⁹¹⁰¹¹¹²⁴,Giraud Emilie⁹¹⁰¹¹¹²⁴^ORCID,Dockrell David H.¹³¹⁴¹⁵²¹⁶^ORCID,Cameron Neil R.⁶⁷⁸⁴^ORCID,Wiese Martin¹⁷¹⁸¹⁹⁴^ORCID,Yakob Laith⁹¹⁰¹¹¹²⁴^ORCID,Rogers Matthew E.⁹¹⁰¹¹¹²⁴^ORCID,Geoghegan Mark¹²³⁴²⁰^ORCID

Affiliation:

1. Department of Physics and Astronomy

2. The University of Sheffield

3. Sheffield S3 7RH

4. UK

5. Insight SFI Research Centre for Data Analytics

6. Department of Chemistry

7. Durham University

8. Durham DH1 3LE

9. Faculty of Infectious and Tropical Diseases

10. Department of Disease Control

11. London School of Hygiene and Tropical Medicine

12. London WC1E 7HT

13. Department of Infection

14. Immunity & Cardiovascular Disease

15. The Medical School

16. Sheffield Teaching Hospitals

17. Strathclyde Institute of Pharmacy and Biomedical Sciences

18. University of Strathclyde

19. Glasgow G4 0RE

20. School of Engineering

Abstract

Force spectroscopy was used to measure the adhesion of Leishmania to synthetic mimics of galectins on the sand fly midgut.

Funder

Consejo Nacional de Ciencia y Tecnología

Leverhulme Trust

Eusko Jaurlaritza

Medical Research Council

Engineering and Physical Sciences Research Council

Biotechnology and Biological Sciences Research Council

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/SC/D0SC03298K

Reference64 articles.

1. Leishmaniasis Worldwide and Global Estimates of Its Incidence

2. Transmission of Leishmania metacyclic promastigotes by phlebotomine sand flies

3. World Health Organization , Control of the Leishmaniases , WHO , Geneva , 2010

4. Recent Developments in Drug Discovery for Leishmaniasis and Human African Trypanosomiasis

5. Leishmaniasis chemotherapy—challenges and opportunities

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