Protein-induced fluorescence enhancement for a simple and universal detection of protein/small molecule interactions-Reference-Cited by-同舟云学术

Protein-induced fluorescence enhancement for a simple and universal detection of protein/small molecule interactions

Published:2018 Issue:70 Volume:8 Page:39913-39917
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Kim Hansol¹²³⁴,Lee Chang Yeol¹²³⁴,Song Jayeon¹²³⁴,Yoon Junhyeok¹²³⁴,Park Ki Soo⁵⁶⁷⁸⁴^ORCID,Park Hyun Gyu¹²³⁴^ORCID

Affiliation:

1. Department of Chemical and Biomolecular Engineering (BK 21+ Program)

2. KAIST

3. Daejeon 305-701

4. Republic of Korea

5. Department of Biological Engineering

6. College of Engineering

7. Konkuk University

8. Seoul 05029

Abstract

We herein describe a novel and efficient method for the detection of protein/small molecule (SM) interactions, which relies on the protein-induced fluorescence enhancement (PIFE).

Funder

Ministry of Science, ICT and Future Planning

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/RA/C8RA08515C

Reference34 articles.

1. Cancer cell death induced by novel small molecules degrading the TACC3 protein via the ubiquitin–proteasome pathway

2. Discovering potent and selective reversible inhibitors of enzymes in complex proteomes

3. Overexpression of folate binding protein in ovarian cancers

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