Interspecies differences in the cytochrome P450 activity of hepatocytes exposed to PLGA and silica nanoparticles: an in vitro and in vivo investigation-Reference-Cited by-同舟云学术

Interspecies differences in the cytochrome P450 activity of hepatocytes exposed to PLGA and silica nanoparticles: an in vitro and in vivo investigation

Published:2018 Issue:11 Volume:10 Page:5171-5181
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

Cornu Raphaël¹²³⁴,Rougier Nathalie⁵⁶⁴,Pellequer Yann¹²³⁴,Lamprecht Alf¹²³⁴⁷,Hamon Paul¹²³⁴,Li Ruoya⁵⁶⁴,Beduneau Arnaud¹²³⁴,Martin Hélène¹²³⁴^ORCID

Affiliation:

1. PEPITE EA4267

2. Univ. Bourgogne Franche-Comté

3. F-25000 Besançon

4. France

5. Biopredic International

6. 35760 Saint-Grégoire

7. Department of Pharmaceutical Technology and Biopharmaceutics

Abstract

This study emphasizes the interest to set up relevant in vitro models using human hepatic cells to evaluate the hepatotoxicity of nanomedicines.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2018/NR/C8NR00226F

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