Target delivery of β-cyclodextrin/paclitaxel complexed fluorescent carbon nanoparticles: externally NIR light and internally pH sensitive-mediated release of paclitaxel with bio-imaging

Author:

Sharker Shazid Md.1234,Kim Sung Min5674,Kim Sung Han8674,In Insik86749,Lee Haeshin1234,Park Sung Young56748

Affiliation:

1. Department of Chemistry

2. Korea Advanced Institute of Science and Technology (KAIST)

3. Daejeon 305-701

4. Republic of Korea

5. Department of Chemical and Biological Engineering

6. Korea National University of Transportation

7. Chungju 380-702

8. Department of IT Convergence

9. Department of Polymer Science and Engineering

Abstract

The carbonized fluorescence hyaluronic acid (HA-FCN) for triggered target bioimaging ability have conjugated with β-cyclodextrin (CD) to release PTX by intracellular pH as well as remote photothermal NIR light control.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

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