Didymorenloids A and B, two polycyclic cyclopenta[<i>b</i>]fluorene-type alkaloids with anti-hepatoma activity from the mangrove endophytic fungus <i>Didymella</i> sp. CYSK-4-Reference-Cited by-同舟云学术

Didymorenloids A and B, two polycyclic cyclopenta[b]fluorene-type alkaloids with anti-hepatoma activity from the mangrove endophytic fungus Didymella sp. CYSK-4

Published:2024 Issue:6 Volume:11 Page:1706-1712
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Chen Yan¹²^ORCID,Yang Wencong³,Zhu Ge⁴,Wang Guisheng²,Chen Tao²,Li Hang³^ORCID,Yuan Jie⁴,She Zhigang²^ORCID

Affiliation:

1. School of Pharmacy, An Hui Medical University, Hefei, 230032, P. R. China

2. School of Chemistry, Sun Yat-Sen University, Guangzhou, 510275, P. R. China

3. School of Pharmaceutical Sciences, Sun Yat-Sen University, 510006, P. R. China

4. Department of Biochemistry, Zhongshan School of Medicine, Sun Yat-Sen University, 510080, P. R. China

Abstract

Molecular networking guidance lead to the isolation of a new cyclopenta[b]fluorene-type alkaloid didymorenloid A (1), containing an unprecedented 6/5/6/5/13(6)/5/5/5-fused ring system, from the mangrove endophytic fungus Didymella sp. CYSK-4.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Anhui Province

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/QO/D3QO01917A

Reference24 articles.

1. Embellicines A and B: Absolute Configuration and NF-κB Transcriptional Inhibitory Activity

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3. Ascomylactams A–C, Cytotoxic 12- or 13-Membered-Ring Macrocyclic Alkaloids Isolated from the Mangrove Endophytic Fungus Didymella sp. CYSK-4, and Structure Revisions of Phomapyrrolidones A and C

4. Brønsted acid-promoted thiazole synthesis under metal-free conditions using sulfur powder as the sulfur source

5. Embellicines C-E: Macrocyclic Alkaloids with a Cyclopenta[b]fluorene Ring System from the Fungus Sarocladium sp.

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