Recent development of biotin conjugation in biological imaging, sensing, and target delivery

Author:

Ren Wen Xiu1234,Han Jiyou56728,Uhm Soojin1234,Jang Yu Jin56728,Kang Chulhun910114,Kim Jong-Hoon56728,Kim Jong Seung1234

Affiliation:

1. Department of Chemistry

2. Korea University

3. Seoul 136-701

4. South Korea

5. Laboratory of Stem Cells and Tissue Regeneration

6. Division of Biotechnology

7. College of Life Sciences & Biotechnology

8. Seoul

9. Graduate School of Medical Science

10. Kyung Hee University

11. Yongin

Abstract

Biotin is a promising targeting unit for carcinoma cell lines and the avidin–biotin technology is an exceedingly flexible tool for pretargeting and vector targeting. Thus, biotin conjugation is an attractive choice for achieving site-specific sensing, labeling, and delivery.

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

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