α-Trideuteration of methylarenes
Author:
Affiliation:
1. Department of Chemistry
2. University of Science and Technology of China
3. Hefei
4. China
5. Institute of Advanced Synthesis
6. School of Chemistry and Molecular Engineering
7. Nanjing Tech University
8. Nanjing 211816
Abstract
An efficient and practical transition metal free α-trideuteration of methylarenes was developed.
Funder
National Natural Science Foundation of China
Fundamental Research Funds for the Central Universities
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2021/QO/D1QO00265A
Reference19 articles.
1. The Renaissance of H/D Exchange
2. C−H Functionalisation for Hydrogen Isotope Exchange
3. Nickel and Nucleophilic Cobalt-Catalyzed Trideuteriomethylation of Aryl Halides Using Trideuteriomethyl p-Toluenesulfonate
4. Nickel-Catalyzed Methylation of Aryl Halides with Deuterated Methyl Iodide
5. A facile and general acid-catalyzed deuteration at methyl groups of N-heteroarylmethanes
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