Total stepwise solid-phase synthesis of peptide–oligonucleotide conjugates using side-chain Boc/<i>t</i>Bu protecting groups-Reference-Cited by-同舟云学术

Total stepwise solid-phase synthesis of peptide–oligonucleotide conjugates using side-chain Boc/tBu protecting groups

Published:2023 Issue:39 Volume:59 Page:5839-5842
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Wang Tao¹²,Cao Xiuxiu¹²,Zheng Yong³,Chen Chenchen³,Zhou Li³,Sun Demeng²,Fang Gemin⁴^ORCID,Tian Changlin¹²^ORCID

Affiliation:

1. High Magnetic Field Laboratory, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei 230031, P. R. China

2. Hefei National Laboratory for Physical Sciences at the Microscale, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230026, P. R. China

3. Hefei KS-V peptide biological technology CO., Ltd., Hefei, P. R. China

4. Institutes of Physical Science and Information Technology, Institute of Health Sciences, Anhui University, Hefei, 230601, P. R. China

Abstract

A practical strategy for the total stepwise solid-phase synthesis of peptide–oligonucleotide conjugates was developed, which will expand the applicability of this strategy in the preparation of peptide–oligonucleotide conjugates.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2023/CC/D3CC00868A

Reference32 articles.

1. Splice-switching antisense oligonucleotides as therapeutic drugs

2. Therapeutic RNA-silencing oligonucleotides in metabolic diseases

3. Oligonucleotide therapies for disorders of the nervous system

4. Recent Advances in Oligonucleotide Therapeutics in Oncology

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