High-resolution DNA size enrichment using a magnetic nano-platform and application in non-invasive prenatal testing

Author:

Zhang Bo12345ORCID,Zhao Shuting12367,Wan Hao123,Liu Ying4578,Zhang Fei45789,Guo Xin12345,Zeng Wenqi12367,Zhang Haiyan4578,Zeng Linghua4578,Qu Jiale678,Wu Ben-Qing10117128,Wan Xinhong1378,Cantor Charles R.1231415,Ge Dongliang12345

Affiliation:

1. Apostle Inc.

2. San Jose

3. USA

4. School of Innovation and Entrepreneurship

5. Southern University of Science and Technology

6. Shenzhen Apostle-Sustech Ltd

7. Shenzhen

8. China

9. School of Public Health

10. Department of Pediatrics

11. University of Chinese Academy of Sciences-Shenzhen Hospital

12. Guangdong

13. Longgang District Maternity and Child Healthcare Hospital

14. Department of Biomedical Engineering

15. Boston University

Abstract

A magnetic nano-platform that enriches cell-free fetal DNA from maternal blood with superior 20 bp resolution for size separation and high yield.

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

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