<i>In silico</i> identification of multi-target inhibitors from medicinal fungal metabolites against the base excision repair pathway proteins of African swine fever virus-Reference-Cited by-同舟云学术

In silico identification of multi-target inhibitors from medicinal fungal metabolites against the base excision repair pathway proteins of African swine fever virus

Published:2024 Issue:14 Volume:14 Page:10039-10055
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Macalalad Mark Andrian B.¹^ORCID,Orosco Fredmoore L.¹²³^ORCID

Affiliation:

1. Virology and Vaccine Research and Development Program, Department of Science and Technology - Industrial Technology Development Institute, Taguig, Metro Manila, 1632, Philippines

2. S&T Fellows Program, Department of Science and Technology, Taguig, Metro Manila, 1632, Philippines

3. Department of Biology, College of Arts and Sciences, University of the Philippines Manila, Manila, Metro Manila, 1000, Philippines

Abstract

Through in silico methods, three fungal metabolites, namely cochlactone A, antcamphin M, and methyl ganoderate E, exhibited potential multi-target inhibitory activity against African swine fever virus (ASFV) base excision repair proteins.

Funder

Philippine Council for Agriculture, Aquatic and Natural Resources Research and Development

Department of Science and Technology, Philippines

Department of Science and Technology, Republic of the Philippines

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/RA/D4RA00819G

Reference57 articles.

1. African swine fever – A review of current knowledge

2. Structure and function of African swine fever virus proteins: Current understanding

3. The global economic impact of ASF , https://bulletin.woah.org/?panorama=02-2-2-2020-1-economic , accessed 7 November 2023

4. G.Wang , ASF in China: Current Status, Control Measures and Experience , https://www.woah.org/app/uploads/2023/04/12-4-gongmin-wang-slides.pdf , accessed 18 October 2023

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