A medium-firm drug-candidate library of cryptand-like structures on T7 phage: design and selection of a strong binder for Hsp90-Reference-Cited by-同舟云学术

A medium-firm drug-candidate library of cryptand-like structures on T7 phage: design and selection of a strong binder for Hsp90

Published:2021 Issue:1 Volume:19 Page:146-150
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Mochizuki Kazuto¹²³⁴⁵,Matsukura Lisa⁶⁷⁸⁹¹⁰,Ito Yuji¹¹¹²¹³¹⁴¹⁰,Miyashita Naoyuki⁶⁷⁸⁹¹⁰^ORCID,Taki Masumi¹²³⁴⁵^ORCID

Affiliation:

1. Department of Engineering Science

2. Bioscience and Technology Program

3. The Graduate School of Informatics and Engineering

4. The University of Electro-Communications (UEC)

5. Chofu

6. Department of Biological Systems Engineering

7. Graduate School of Biology-Oriented Science and Technology

8. KINDAI University

9. Kinokawa

10. Japan

11. Department of Chemistry and Bioscience

12. Graduate School of Science and Engineering

13. Kagoshima University

14. Kagoshima

Abstract

We designed and synthesized a library of cryptand-like structures on the T7 phage; a strong binder for a cancer-related protein was selected from the library.

Funder

Japan Society for the Promotion of Science

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/OB/D0OB01855D

Reference62 articles.

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