Grape seed extract supplementation modulates hepatic lipid metabolism in rats. Implication of PPARβ/δ-Reference-Cited by-同舟云学术

Grape seed extract supplementation modulates hepatic lipid metabolism in rats. Implication of PPARβ/δ

Published:2022 Issue:21 Volume:13 Page:11353-11368
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Guisantes-Batan Eduardo¹²^ORCID,Mazuecos Lorena³⁴^ORCID,Rubio Blanca³⁴,Pereira-Caro Gema⁵⁶^ORCID,Moreno-Rojas José Manuel⁵⁶^ORCID,Andrés Antonio³⁴^ORCID,Gómez-Alonso Sergio¹²^ORCID,Gallardo Nilda³⁴^ORCID

Affiliation:

1. Regional Institute for Applied Scientific Research, University of Castilla-La Mancha, Avenida Camilo José Cela 1B, 13071 Ciudad Real, Spain

2. Department of Analytical Chemistry and Food Technology, Faculty of Chemical Sciences and Technologies, University of Castilla-La Mancha, Avenida Camilo José Cela 10, 13071 Ciudad Real, Spain

3. Regional Centre for Biomedical Research (CRIB), University of Castilla-La Mancha, 13071 Ciudad Real, Spain

4. Biochemistry Section, Faculty of Chemical Sciences and Technologies, University of Castilla-La Mancha, Avenida Camilo José Cela 10, 13071 Ciudad Real, Spain

5. Department of Agroindustry and Food Quality, Andalusian Institute of Agricultural and Fisheries Research and Training (IFAPA), Avenida Menendez-Pidal, SN, 14004 Córdoba, Spain

6. Foods for Health Group, Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), Córdoba, Spain

Abstract

Grape seed extract supplementationat low doses (25 mg per kg BW per day) modulates the transcriptional programs that controls the hepatic lipid metabolism in lean normolipidemic Wistar rats through PPARβ/δ activation.

Funder

European Social Fund

Universidad de Castilla-La Mancha

European Regional Development Fund

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2022/FO/D2FO02199D

Reference74 articles.

1. Global Updates on Cardiovascular Disease Mortality Trends and Attribution of Traditional Risk Factors