The anti-hepatocellular carcinoma effects of polysaccharides from <i>Ganoderma lucidum</i> by regulating macrophage polarization <i>via</i> the MAPK/NF-κB signaling pathway-Reference-Cited by-同舟云学术

The anti-hepatocellular carcinoma effects of polysaccharides from Ganoderma lucidum by regulating macrophage polarization via the MAPK/NF-κB signaling pathway

Published:2023 Issue:7 Volume:14 Page:3155-3168
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Li Guo-li¹²^ORCID,Tang Jia-feng¹²,Tan Wen-li²,Zhang Tao³²,Zeng Di¹,Zhao Shuang¹,Ran Jian-hua³,Li Jing¹,Wang Ya-ping¹,Chen Di-long¹²

Affiliation:

1. Lab of Stem Cell and Tissue Engineering, Department of Histology and Embryology, Chongqing Medical University, Chongqing, PR China

2. Chongqing Key Laboratory of Development and Utilization of Genuine Medicinal Materials in Three Gorges Reservoir Area, Chongqing Three Gorges Medical College, Chongqing, PR China

3. Neuroscience Research Center, College of Basic Medicine, Chongqing Medical University, Chongqing, PR China

Abstract

Ganoderma lucidum polysaccharide (GLPS) can inhibit hepatocellular carcinoma (HCC). But the mechanism of GLPS's effect is little known. This data showed that GLPS can regulate MAPK/NF-κB signaling responsible for M1 polarization in anti-HCC.

Funder

Chongqing Municipal Education Commission Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2023/FO/D2FO02191A

Reference39 articles.

1. Viola yedoensis Makino formula alleviates DNCB-induced atopic dermatitis by activating JAK2/STAT3 signaling pathway and promoting M2 macrophages polarization

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3. Cancer cell and macrophage cross-talk in the tumor microenvironment

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