A novel 18F-labelled high affinity agent for PET imaging of the translocator protein-Reference-Cited by-同舟云学术

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A novel 18F-labelled high affinity agent for PET imaging of the translocator protein

Published:2015 Issue:8 Volume:6 Page:4772-4777
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Blair Adele¹²³⁴⁵,Zmuda Filip¹²³⁴⁵,Malviya Gaurav⁶⁷⁸⁵,Tavares Adriana A. S.⁹¹⁰¹¹,Tamagnan Gilles D.⁹¹⁰¹¹,Chalmers Anthony J.¹²¹³³¹⁴⁵,Dewar Deborah¹⁵¹⁶¹⁷³⁴,Pimlott Sally L.¹⁸¹⁹²⁰⁵,Sutherland Andrew¹²³⁴⁵

Affiliation:

1. WestCHEM

2. School of Chemistry

3. University of Glasgow

4. Glasgow G12 8QQ

5. UK

6. Nuclear Imaging Facility

7. The Beatson Institute for Cancer Research

8. Glasgow G61 1BD

9. Molecular NeuroImaging,

10. LLC

11. USA

12. Wolfson Whol Cancer Research Centre

13. Institute of Cancer Sciences

14. Glasgow G61 1QH

15. Institute of Neuroscience and Psychology

16. College of Medical

17. Veterinary and Life Sciences

18. West of Scotland Radionuclide Dispensary

19. University of Glasgow and North Glasgow University Hospital NHS Trust

20. Glasgow G11 6NT

Abstract

A novel ¹⁸F-labelled quinoline-2-carboxamide has been characterised as a novel PET imaging agent for the translocator protein.

Funder

Scottish Funding Council

EPSRC

University Of Glasgow

Chief Scientist Office

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/SC/C5SC01647A

Reference37 articles.

1. Molecular tracers for the PET and SPECT imaging of disease

2. Molecular Imaging with PET

3. Chemistry with [ 18 F]Fluoride Ion

4. Synthesis of11C,18F,15O, and13N Radiolabels for Positron Emission Tomography

5. Methods for the Incorporation of Carbon-11 To Generate Radiopharmaceuticals for PET Imaging

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