Synthesis and biochemical characterization of quasi-stable trimer models of full-length amyloid β40 with a toxic conformation-Reference-Cited by-同舟云学术

Synthesis and biochemical characterization of quasi-stable trimer models of full-length amyloid β40 with a toxic conformation

Published:2019 Issue:2 Volume:55 Page:182-185
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Irie Yumi¹²³⁴⁵,Hanaki Mizuho¹²³⁴⁵,Murakami Kazuma¹²³⁴⁵^ORCID,Imamoto Tsuneo⁶⁷⁵,Furuta Takumi⁸³⁹⁵,Kawabata Takeo⁸³⁹⁵^ORCID,Kawase Taiji¹⁰¹¹⁵,Hirose Kenji¹⁰¹¹⁵,Monobe Yoko¹²¹³¹⁴⁵,Akagi Ken-ichi¹²¹³¹⁴⁵,Yanagita Ryo C.¹⁵¹⁶¹⁷¹⁸⁵^ORCID,Irie Kazuhiro¹²³⁴⁵^ORCID

Affiliation:

1. Division of Food Science and Biotechnology

2. Graduate School of Agriculture

3. Kyoto University

4. Kyoto 606-8502

5. Japan

6. Nippon Chemical Industrial Co. Ltd

7. Tokyo 136-8515

8. Institute for Chemical Research

9. Kyoto 611-0011

10. Nihon Waters K. K.

11. Tokyo 140-0001

12. National Institute of Biomedical Innovation

13. Health and Nutrition

14. Osaka 567-0085

15. Department of Applied Biological Science

16. Faculty of Agriculture

17. Kagawa University

18. Kagawa 761-0795

Abstract

The only trimer model to exhibit weak but significant neurotoxicity against SH-SY5Y cells was the one which was linked at position 38.

Funder

Japan Society for the Promotion of Science

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2019/CC/C8CC08618D

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