Late-stage deuteration of13C-enriched substrates forT1prolongation in hyperpolarized13C MRI-Reference-Cited by-同舟云学术

Late-stage deuteration of13C-enriched substrates forT1prolongation in hyperpolarized13C MRI

Published:2018 Issue:41 Volume:54 Page:5233-5236
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Taglang Céline¹²³⁴^ORCID,Korenchan David E.¹²³⁴^ORCID,von Morze Cornelius¹²³⁴,Yu Justin¹²³⁴,Najac Chloé¹²³⁴,Wang Sinan¹²³⁴,Blecha Joseph E.¹²³⁴,Subramaniam Sukumar¹²³⁴,Bok Robert¹²³⁴,VanBrocklin Henry F.¹²³⁴,Vigneron Daniel B.¹²³⁴,Ronen Sabrina M.¹²³⁴,Sriram Renuka¹²³⁴,Kurhanewicz John¹²³⁴,Wilson David M.¹²³⁴,Flavell Robert R.¹²³⁴^ORCID

Affiliation:

1. Department of Radiology and Biomedical Imaging

2. University of California

3. San Francisco

4. USA

Abstract

Deuteration on¹³C-enriched substrates led to increases inT₁, yielding improvements in imaging parameters.

Funder

Efficacy and Mechanism Evaluation Programme

U.S. Department of Defense

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2018/CC/C8CC02246A

Reference43 articles.

1. Nuclear Magnetic Resonance of Laser-Polarized Noble Gases in Molecules, Materials, and Organisms

2. Real-Time Molecular Imaging of Tricarboxylic Acid Cycle Metabolism in Vivo by Hyperpolarized 1-13C Diethyl Succinate

3. PASADENA Hyperpolarization of Succinic Acid for MRI and NMR Spectroscopy

4. Metabolic Imaging of Patients with Prostate Cancer Using Hyperpolarized [1- 13 C]Pyruvate

5. Molecular imaging with endogenous substances

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