A visible-light mediated three-component radical process using dithiocarbamate anion catalysis-Reference-Cited by-同舟云学术

A visible-light mediated three-component radical process using dithiocarbamate anion catalysis

Published:2019 Issue:21 Volume:10 Page:5484-5488
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Cuadros Sara¹²³⁴,Horwitz Matthew A.¹²³⁴,Schweitzer-Chaput Bertrand¹²³⁴^ORCID,Melchiorre Paolo¹²³⁴⁵^ORCID

Affiliation:

1. ICIQ – Institute of Chemical Research of Catalonia

2. The Barcelona Institute of Science and Technology

3. Tarragona

4. Spain

5. IIT – Istituto Italiano di Tecnologia

Abstract

A three-component radical process is reported that, by coupling alkyl chlorides, maleimides, and heteroaromatic fragments, installs multiple biologically relevant heterocycles within complex cascade products. This method, which generates radicals via an S_N2-based photochemical catalytic mechanism, activates substrates incompatible with or inert to classical radical-generating strategies.

Funder

H2020 European Research Council

Ministerio de Ciencia e Innovación

Agència de Gestió d’Ajuts Universitaris i de Recerca

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/SC/C9SC00833K

Reference41 articles.

1. Cascade Reactions in Total Synthesis

2. L. F. Tietze , G.Brasche and K. M.Gericke , in Domino Reactions in Organic Synthesis , Wiley-VCH , Weinheim , 2006

3. Catalysis of Radical Reactions: A Radical Chemistry Perspective

4. Radicals: Reactive Intermediates with Translational Potential

5. V. Liautard and Y.Landais , ‘Free-radical Multicomponent Processes’ , in Multicomponent Reactions in Organic Synthesis , ed. J. Zhu , Q. Wang and M.-X. Wang , Wiley-VCH , 2015 , ch. 14, pp. 401–438

Cited by 45 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Photochemical Deoxygenative Hydroalkylation of Unactivated Alkenes Promoted by a Nucleophilic Organocatalyst;Angewandte Chemie;2024-01-11

2. Photochemical Deoxygenative Hydroalkylation of Unactivated Alkenes Promoted by a Nucleophilic Organocatalyst;Angewandte Chemie International Edition;2024-01-08

3. Facile synthesis of 3-(pyrazol-1-yl) succinimides from Ag ₂ CO ₃ -catalyzed aza-Michael addition of pyrazoles to maleimides;Synthetic Communications;2023-10-26

4. Photo‐induced Desulfurative Processes for Carbon Radical Generation;ChemCatChem;2023-09-13

5. Magnetically separable tris(N,N-difurfuryldithiocarbamato-S,S’)iron(III), micro and nano iron sulfide photocatalysts for the degradation of dyes;Journal of Molecular Structure;2023-08