The sustainable synthesis of levetiracetam by an enzymatic dynamic kinetic resolution and an ex-cell anodic oxidation-Reference-Cited by-同舟云学术

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The sustainable synthesis of levetiracetam by an enzymatic dynamic kinetic resolution and an ex-cell anodic oxidation

Published:2021 Issue:1 Volume:23 Page:388-395
ISSN:1463-9262
Container-title:Green Chemistry
language:en
Short-container-title:Green Chem.

Author:

Arndt Sebastian¹²³⁴,Grill Birgit⁵⁶⁷,Schwab Helmut⁵⁶⁷⁸⁹,Steinkellner Georg⁵⁶⁷¹⁰¹¹,Pogorevčnik Urška⁵⁶⁷,Weis Dominik¹²³⁴,Nauth Alexander M.¹²³⁴,Gruber Karl⁵⁶⁷^ORCID,Opatz Till¹²³⁴^ORCID,Donsbach Kai¹²¹³⁴,Waldvogel Siegfried R.¹²³⁴^ORCID,Winkler Margit⁵⁶⁷⁸⁹^ORCID

Affiliation:

1. Department of Chemistry

2. Johannes Gutenberg University Mainz

3. 55128 Mainz

4. Germany

5. acib – Austrian Centre of Industrial Biotechnology

6. A-8010 Graz

7. Austria

8. Institute of Molecular Biotechnology

9. Graz University of Technology

10. Innophore GmbH

11. 8010 Graz

12. PharmaZell GmbH

13. 83064 Raubling

Abstract

Levetiracetam is an active pharmaceutical ingredient widely used to treat epilepsy.

Funder

European Commission

Deutsche Forschungsgemeinschaft

Österreichische Forschungsförderungsgesellschaft

Publisher

Royal Society of Chemistry (RSC)

Subject

Pollution,Environmental Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/GC/D0GC03358H

Reference89 articles.

1. Treatment, Therapy and Management of Metabolic Epilepsy: A Systematic Review

2. UCB, Integrated Annual Report, 2019. https://reports.ucb.com/2019/integrated-annual-report/data-reporting/financial-data.html&hash;accordion2

3. A short enantioselective synthesis of the antiepileptic agent, levetiracetam based on proline-catalyzed asymmetric α-aminooxylation

4. Chiral oxazolidinones as electrophiles: intramolecular cyclization reactions with carbanions and preparation of functionalized lactams

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4. Peroxodicarbonate – a renaissance of an electrochemically generated green oxidizer;Chemical Communications;2024

5. Development of MoS2 flower-adorned pencil graphite electrode for electro-kinetic investigations and voltammetric quantification of anti-epileptic drug levetiracetam;Journal of Applied Electrochemistry;2023-11-20

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