A hypoxia-specific and mitochondria-targeted anticancer theranostic agent with high selectivity for cancer cells-Reference-Cited by-同舟云学术

A hypoxia-specific and mitochondria-targeted anticancer theranostic agent with high selectivity for cancer cells

Published:2018 Issue:16 Volume:6 Page:2413-2416
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Hu Mingxing¹²³⁴⁵,Yang Chao¹²³⁴⁵,Luo Yi¹²³⁴⁵,Chen Fan¹²³⁴⁵,Yang Fangfang¹²³⁴⁵,Yang Shuping¹²³⁴⁵,Chen Hao¹²³⁴⁵,Cheng Zhiqiang⁶⁷⁸⁹^ORCID,Li Kun¹²³⁴⁵^ORCID,Xie Yongmei¹²³⁴⁵^ORCID

Affiliation:

1. State Key Laboratory of Biotherapy and Cancer Center

2. West China Hospital

3. Sichuan University

4. and Collaborative Innovation Center for Biotherapy

5. Chengdu

6. Department of Pharmacology and Molecular Sciences

7. Johns Hopkins University School of Medicine

8. Baltimore

9. USA

Abstract

A novel hypoxia-specific and mitochondria-targeted theranostic agent,HMX-1, was reported with certified anti-cancer efficiencyin vitroandin vivo.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2018/TB/C8TB00546J

Reference28 articles.

1. Hypoxia — a key regulatory factor in tumour growth

2. The Histological Structure of Some Human Lung Cancers and the Possible Implications for Radiotherapy

3. Hallmarks of Cancer: The Next Generation

4. Tumour hypoxia, chemotherapeutic resistance and hypoxia-related therapies

5. Exploiting tumour hypoxia in cancer treatment

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