Single chain variable fragment fused to maltose binding protein: a modular nanocarrier platform for the targeted delivery of antitumorals-Reference-Cited by-同舟云学术

Single chain variable fragment fused to maltose binding protein: a modular nanocarrier platform for the targeted delivery of antitumorals

Published:2021 Issue:5 Volume:9 Page:1728-1738
ISSN:2047-4830
Container-title:Biomaterials Science
language:en
Short-container-title:Biomater. Sci.

Author:

Reche-Perez Francisco J.¹²³⁴⁵^ORCID,Plesselova Simona¹²³⁴⁵,De los Reyes-Berbel Eduardo⁶⁷⁸³⁴,Ortega-Muñoz Mariano¹²³⁴⁵,Lopez-Jaramillo Francisco J.⁶⁷⁸³⁴^ORCID,Hernandez-Mateo Fernando⁶⁷⁸³⁴^ORCID,Santoyo-Gonzalez Francisco⁶⁷⁸³⁴^ORCID,Salto-Gonzalez Rafael¹²³⁴⁵^ORCID,Giron-Gonzalez Maria D.¹²³⁴⁵^ORCID

Affiliation:

1. Department of Biochemistry and Molecular Biology II

2. School of Pharmacy

3. University of Granada

4. E-18071 Granada

5. Spain

6. Department of Organic Chemistry

7. School of Sciences

8. Biotechnology Institute

Abstract

A modular platform for targeted delivery was based on a single chain variable (ScFv) fragment fused to maltose-binding protein (MBP). Using different maltosylated ligands it is likely to target, transport drugs, or deliver genes to specific cells.

Funder

Ministerio de Economía, Industria y Competitividad, Gobierno de España

European Regional Development Fund

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

Link

http://pubs.rsc.org/en/content/articlepdf/2021/BM/D0BM01903H

Reference60 articles.

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