Highly efficient regio-selective ring-opening nucleophilic fluorination of aziridines and azetidines: access to β- or γ-fluorinated amino acid derivatives-Reference-Cited by-同舟云学术

Highly efficient regio-selective ring-opening nucleophilic fluorination of aziridines and azetidines: access to β- or γ-fluorinated amino acid derivatives

Published:2019 Issue:15 Volume:17 Page:3797-3804
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Zhu Liping¹²³⁴,Xiong Jiale¹²³⁴,An Junkai⁵⁶⁷⁸⁴,Chen Nannan¹²³⁴,Xue Jijun⁵⁶⁷⁸⁴,Jiang Xianxing¹²³⁴^ORCID

Affiliation:

1. School of Pharmaceutical Sciences

2. Sun Yat-Sen University

3. Guangzhou

4. China

5. State Key Laboratory of Applied Organic Chemistry

6. College of Chemistry and Chemical Engineering

7. Lanzhou University

8. Lanzhou

Abstract

The strategy is mild and efficient, useful in synthesizing β- or γ-fluorinated amines and enantioenriched β-fluoro-α-amino acid derivatives.

Funder

National Natural Science Foundation of China

Guangdong Innovative and Entrepreneurial Research Team Program

Recruitment Program of Global Experts

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/OB/C9OB00172G

Reference64 articles.

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4. Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas

5. Fluorine in medicinal chemistry

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