Highly efficient regio-selective ring-opening nucleophilic fluorination of aziridines and azetidines: access to β- or γ-fluorinated amino acid derivatives

Author:

Zhu Liping1234,Xiong Jiale1234,An Junkai56784,Chen Nannan1234,Xue Jijun56784,Jiang Xianxing1234ORCID

Affiliation:

1. School of Pharmaceutical Sciences

2. Sun Yat-Sen University

3. Guangzhou

4. China

5. State Key Laboratory of Applied Organic Chemistry

6. College of Chemistry and Chemical Engineering

7. Lanzhou University

8. Lanzhou

Abstract

The strategy is mild and efficient, useful in synthesizing β- or γ-fluorinated amines and enantioenriched β-fluoro-α-amino acid derivatives.

Funder

National Natural Science Foundation of China

Guangdong Innovative and Entrepreneurial Research Team Program

Recruitment Program of Global Experts

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

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