Asymmetric total synthesis of (+)-asenapine-Reference-Cited by-同舟云学术

Asymmetric total synthesis of (+)-asenapine

Published:2019 Issue:12 Volume:17 Page:3225-3231
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Szcześniak Piotr¹²³⁴^ORCID,Staszewska-Krajewska Olga⁵⁶⁷⁴,Mlynarski Jacek⁵⁶⁷⁴^ORCID

Affiliation:

1. Faculty of Chemistry

2. Jagiellonian University

3. 30-387 Kraków

4. Poland

5. Institute of Organic Chemistry

6. Polish Academy of Sciences

7. 01-224 Warsaw

Abstract

Asymmetric total synthesis of (+)-asenapine involving the organocatalytic Michael addition reaction and subsequent Zn-promoted reductive cyclization as the key steps.

Funder

Narodowe Centrum Nauki

Fundacja na rzecz Nauki Polskiej

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/OB/C9OB00178F

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