pH-Responsive Au@Pd bimetallic core–shell nanorods for enhanced synergistic targeted photothermal-augmented nanocatalytic therapy in the second near-infrared window

Author:

Tang Zhe1,Ali Israt2ORCID,Hou Yike1,Akakuru Ozioma Udochukwu3,Zhang Quan1,Mushtaq Asim1ORCID,Zhang Han1ORCID,Lu Yuguang1,Ma Xuehua4ORCID,Ge Jian5,Iqbal M. Zubair1ORCID,Kong Xiangdong1ORCID

Affiliation:

1. Institute of Smart Biomedical Materials, School of Materials Science and Engineering, Zhejiang Sci-Tech University, Hangzhou 310018, China

2. Institute National de la Recherche Scientifique, Énergie Matériaux Télécommunications Research Centre, 1650 Lionel-Boulet Blvd., Varennes, Quebec J3X 1P7, Canada

3. Department of Chemical and Petroleum Engineering, Schulich School of Engineering, University of Calgary, Alberta, Canada

4. Cixi Institute of Biomedical Engineering, CAS Key Laboratory of Magnetic Materials and Devices, Key Laboratory of Additive Manufacturing Materials of Zhejiang Province, Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, 1219 Zhongguan West Road, Ningbo, Zhejiang, 315201, China

5. College of Life Sciences, China Jiliang University, 258 XueYuan Street, XiaSha Higher Education Zone, Hangzhou, 310018, Zhejiang Province, China

Abstract

NIR-II-light and pH-responsive Au@Pd core–shell HNRs possessed nanoenzyme-mimicking activity and promising photothermal conversion efficiency, resulting in synergistic tumor therapies (PTT/POD/CAT) to overcome the limitations of traditional chemotherapy.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

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