Dendrosome mediated topical gene silencing by PLK-1 specific siRNA: implication in treatment of skin cancer in mouse model-Reference-Cited by-同舟云学术

Dendrosome mediated topical gene silencing by PLK-1 specific siRNA: implication in treatment of skin cancer in mouse model

Published:2016 Issue:8 Volume:6 Page:6843-6857
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Sherwani Mohd. Asif¹²³⁴,Tufail Saba¹²³⁴,Khan Aijaz Ahmed⁵⁶⁷²³,Owais Mohammad¹²³⁴

Affiliation:

1. Interdisciplinary Biotechnology Unit

2. Aligarh Muslim University

3. Aligarh

4. India

5. Department of Anatomy

6. Jawaharlal Nehru Medical College

7. Faculty of Medicine

Abstract

Topical application of PLK-1 siRNA bearing dendrosomes on DMBA induced skin papillomas in mice exhibit potent anti-cancer effect. The treatment leads to reduced number and sizes of papillomas.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/RA/C5RA15270D

Reference41 articles.

1. Polo-like kinases: a team that plays throughout mitosis

2. Polo-like kinases: positive regulators of cell division from start to finish

3. Polo-like kinase (Plk)1 depletion induces apoptosis in cancer cells

4. Targeting Polo-like Kinase in Cancer Therapy: Fig. 1.

5. RNA Interference in Vitro and in Vivo Using a Novel Chitosan/siRNA Nanoparticle System

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