In situ mucoadhesive hydrogel capturing tripeptide KPV: the anti-inflammatory, antibacterial and repairing effect on chemotherapy-induced oral mucositis-Reference-Cited by-同舟云学术

In situ mucoadhesive hydrogel capturing tripeptide KPV: the anti-inflammatory, antibacterial and repairing effect on chemotherapy-induced oral mucositis

Published:2022 Issue:1 Volume:10 Page:227-242
ISSN:2047-4830
Container-title:Biomaterials Science
language:en
Short-container-title:Biomater. Sci.

Author:

Shao Weifeng¹,Chen Rui¹,Lin Gaolong¹,Ran Kunjie¹,Zhang Yingying¹,Yang Jiaojiao¹,Pan Hanxiao¹,Shangguan Jianxun¹,Zhao Yingzheng¹,Xu Helin¹^ORCID

Affiliation:

1. Department of pharmaceutics, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou City, Zhejiang Province 325035, China

Abstract

In situ mucoadhesive hydrogels with inherent antibacterial activity were constructed from temperature-sensitive PPP as a matrix and EGCG as an adhesion enhancer. The hydrogel was designed for cancer patients with chemotherapy-induced oral mucositis.

Funder

Wenzhou Municipal Science and Technology Bureau

Department of Health of Zhejiang Province

Natural Science Foundation of Zhejiang Province

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

Link

http://pubs.rsc.org/en/content/articlepdf/2022/BM/D1BM01466H

Reference57 articles.

1. New Frontiers in the Pathobiology and Treatment of Cancer Regimen-Related Mucosal Injury